The effects of agitation rate,buffer molarity,and mesh size on the dissolution rate of verapamil hydrochloride from sustainedrelease
matrix tablets were studied using USP Apparatus 3. Eudragit® and Carbopol® were used as rate-retarding polymers in
tablets prepared by wet granulation.The study was conducted to determine whether the drugs exhibit similar release characteristics
when tested under the same dissolution conditions. It was found that the dissolution rate of verapamil hydrochloride
was affected by the variables assessed in these studies.
The Effects of Buffer Molarity,Agitation Rate, and Mesh Size on Verapamil Release from Modified- Release Mini-Tablets Using USP