what is actually mean by pooled sampling in dissolution ?when should we go for a pooled sampling?

sharath.nmims's picture
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keerthiyadav's picture


2

When aliquots of each time point of dissolution for 6
tablets are filtered and combined and then analyzed for drug
release such dissolution is called as Pooled Dissolution.
Simply it means mix aliquots of all six tablets and you have
to estimate the drug release in this combined sample of 6
tablets,after each time interval as per dissolution procedure.
 

it reduces the analytical burden.