Pharma Bloggers

GPAT-2012 KEY

Submitted by Udayvenkat on Mon, 05/07/2012 - 12:40
Dear Friends find the GPAT 2012 KEY GPAT 2012 MODEL KEY (Code: A) 01 A 21 D 41 B 61 B 81 D 101 A 121 D 141 D 02 C 22 A 42 A 62 C 82 B 102 D 122 A 142 B 03 B 23 C 43 A 63 A 83 A 103 A 123 C 143 C 04 A 24 D 44 B 64 B 84 C 104 A 124 B 144 D 05 A 25 C 45 B 65 A 85 C 105 B 125 D 145 C 06 B 26 B 46 B 66 C 86 B 106 B 126 A 146 D 07 C 27 C 47 A 67 D 87 D 107 C 127 A 147 C

47. Tobacco - a nuisense created by man!

Submitted by Bhagavan P S on Tue, 01/10/2012 - 10:43
Thanks to Shiva for a good opening topic for 2012. I wish you are not a smoker or at least a ex-smoker now! Cigarette is one such product that does more harm when used in the right way! Cigarette is the only product on the market that is perhaps exempted from disclosing the contents. There are no quality parameters which you can use to cross check the quality.

43 NATIONAL PHARMACY WEEK

Submitted by Bhagavan P S on Sat, 11/19/2011 - 12:06
I have received quite a good response for my previous blog No. 42. I have many invitations and intimations from various pharmacy bodies including pharmacy colleges. Many have called me over phone expressing their good feel at my suggestion on Domestic drug management and have asked me to suggest some more activity.

Stability testing

Submitted by sailesh on Sun, 08/28/2011 - 14:39
First of all I would like to apologize for not being blogging since a long time. I am some what hectic with M.pharm project submission and job searching by moving to other areas. My mind is not stable and could not concentrate on blogging. I would like to share some of my knowledge on stability testing and its significance.

Technology transfer (Lab to commercial scale):

Submitted by sailesh on Mon, 07/11/2011 - 12:53
I would like to share some basic knowledge about Technology transfer or LTC (Lab to commercial scale) gained during seminar in Bapatla College of pharmacy by Adan Sabir sir (Ex-Vice president Dr.Reddy's Laboratories). It takes much time to transfer a product developed in the laboratory to large scale manufacturing. The example given by him was so simple and everyone can easily understand about the complexity involved in technology transfer. It is easy to cook rice or food for a group of 2 to 4 people. But, to cook rice or food for a group of 100 people or more than that is very difficult.

National seminar on Particulate Drug delivery systems

Submitted by sailesh on Fri, 06/17/2011 - 12:35
Hi friends, I would like to take this opportunity to inform all about the National seminar on "Particulate Drug Delivery systems" on July 9th and 10th in Bapatla College of pharmacy. Oral seminars and Posters are invited from M.pharm students. Please see the attachment for more details.

Modified excipients

Submitted by tegkmurthy on Sun, 05/29/2011 - 05:37

There are several reports indicating that the peformance of a pharmacuetical dosage form is influenced by the changes in suppliers of the same excipient due to the variations in physicochemical properties and quality of excipient. There is increased demand for excipients with pre-determined specifications to control the physical properties of excipients like size, shape, tecture, density and moisture content. Spray dried excipients improves the flow property and freeze dried excipients enhances the dissolution rate.

CO-PROCESSING EXCIPIENTS

Submitted by tegkmurthy on Thu, 05/19/2011 - 05:12
Co-processing excipient is an excipients mixture containing more than one excipient and not prepared by simple physical mixing. These materials are formulated with co-crystallization, co-grinding, co-precipitation, spray drying and common solvent evaporation techniques. The physical properties such as particle size, shape, density may differ from one excipient to another excipient and results segregation and non uniformity. In case of co-processed excipients, the physical properties are well controlled.

Antibiotic resistance – super bug

Submitted by sailesh on Sun, 05/15/2011 - 15:43

Antibiotics are a particular class of anti-microbials. Anti-microbials is a general term used to cover all class of microbes like bacteria, protozoa, fungi and other such organisms. Antibiotic refers to a drug that is generally used against the infections caused due to bacteria. Starting from the pencilins, cephalosporins and other classes, a number of antibiotics that might be natural, semi-synthetic or synthetic ones are being discovered to fight against different type of infections.

Sterility testing-Parenteral Dosage Forms

Submitted by vijay m.pharm bcop on Fri, 05/13/2011 - 07:05

Sterility testing attempts to reveal the presence or absence of viable micro-organisms in a sample number of containers taken from batch of product. Based on results obtained from testing the sample a decision is made as to the sterility of the batch1.

There are two common types of sterility test methods:

Discriminative Dissolution Methods - Significance

Submitted by Kishorecollagen on Sun, 05/08/2011 - 06:52
Dear Bloggers, Invitro dissolution test means the rate and extent of dissolution i.e. amount of drug dissolves in the medium. A dissolution study of dosage form necessities modification in dissolution medium to increase solubility. Since pH of GIT is 1-8 it is necessary to develop the medium where the drug has maximum solubility and exhibits sink condition.

Topics for the month of May

Submitted by tegkmurthy on Sat, 05/07/2011 - 17:20
Leader (Myself): 1) Co-processed excipients 2) modified excipients M.Kishore babu : 1) Discriminative dissolution methods significance 2) Correlation of the college lab experiment with the industry - a necessity G.Sailesh : 1) Antibiotic drug resistance - Super bug 2) Enhancement of dissolution using multiparticulates V.Vijaya kumar: 1) Sterility testing

Coating technique for controlled release

Submitted by tegkmurthy on Mon, 04/25/2011 - 03:07
Coating technique is used to modify the site, rate and extent of release. It can be applied for single unit dosage forms such as tablets/capsules and multiple unit dosage forms like pellets, granules. Aqueous based and organic based solvents can be used for coating. Coating technique can also be applied to achieve a drug release after a set lag time. Coating on multiparticulate system reduces the dose duping compared to single unit system.

PACKING MATERIALS FOR PARENTERALS -GLASS

Submitted by vijay m.pharm bcop on Mon, 04/18/2011 - 16:50

Glass is one of the old and cheapest materials using for the packing of various types of pharmaceutical formuations, especially for the parenteral formulations. It has been used for over 6000 years. Containers for parenteral formulations are made are made as far as possible from the materials that are sufficiently transparent and to permit the visual inspection of the contents.