DNA Nanotechnology

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DNA Nanotechnology

Respirocytes a Medical Nanorobotics

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Quantum Dots

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QUANTUM DOTS

AFM Part II

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Modes of Operation and Applications in Pharmacy and Bio related systems

There are two primary methods for measuring the force between a probe and a sample:

Contact mode and vibrating mode.Contact mode entails a direct quasi-static force versus distance measurement, that is, a rather intimate contact between probe and surface.While producing accurate results, it tends to rapidly damage both probe and surface. Vibrating mode may be either large amplitude,in which the probe contacts the surface on every cycle, or small amplitude non-contact.The latter is generally less stressful on both the probe and surface, and tends to give superior results. It measures more subtle properties ofthe surface.

Pharmaceutical studies using AFM-Part I

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Pharmaceutical studies using AFM-Part I
Microscopic evaluation is important for the design and evaluation of a pharmaceutical product after the steps in the drug formulation process. Efficient investigation of surface structure at nanometer to subangstorm resolution in ambient and liquid environments AFM has been routinely used over two decades in many scientific fields. Pharmaceutical research often consists of a combination of many scientific branches, made a unique viable place for the application of AFM. High resolution three dimensional surface structures, sample conductivity make it a powerful complement to other common analytical techniques currently available. Studies of drug crystal growth, particle Characterization, and tablet coatings in the manufacture of solid dosage forms.

Introduction-AFM