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In this blog let us know about one of the schemes offered for health insurance, this particular scheme is called Voluntary health insurance schemes or private-for-profit schemes

Preformulation:
• a stage of development during which the physicochemical properties of drug substance are characterized.
When?
• If the drug shows sufficient activity in animals & is to be evaluated in humans.
Focus…
• On physicochemical properties of a new compound which may affect the drug performance & development of efficacious dosage form.

We all studied dissolution test as the important thing that mimic the in-vivo fate of drug/dosage form.
Despite the fact that dissolution testing is a fundamental part of drug product development and regulatory approval process, it has been a subject of frequent criticism for its limitations of sometimes being non-discriminating, over-discriminating, and formulation specific IVIVC.

In the year 2009, the when the American government has began to reform the healthcare policies with their focus on health insurance, so, that they are able to provide cover to all the Americans. We in India are still struggling to bring in the policy of health insurance.
In this blog we will come across the definition of health insurance and the various schemes available in India.

Dear Readers,
In this month we the team "BLOGBUSTERS" will provide the best of information on "Healthcare in India"...
Under the vast umbrella of this theme we will be dealing with topics such as:

Health insurance
Micro health insurance
Various techniques of providing quality health care to rural India.

Hope you will enjoy reading on these topics in this month of September.

Mapping is a process which relates Critical Manufacturing Variables (CMV), including formulation, processes, and equipment variables that can significantly affect drug release from the product, to a response surface derived from an in vitro dissolution curve and an in vivo bioavailability data.

A volatile solid (e.g Urethrane or ammonium bicarbonate) is added to a standard, directly compressible formulation.
After the tablet compression,the volatilizable solid is removed by a freeze-drying or heating process.
Water easily penetrates through the pores & promotes rapid disintegration.
e.g. Lyoc and Zydis Tablets

• Hiestand quantify rationally the compaction properties of pharmaceutical powders.
• The results of this work are three indices known as Hiestand Tableting Indices.
– The Strain Index (SI)
– The Bonding Index (BI)
– The Brittle Fracture Index (BFI).
• The SI is a measure of the internal entropy, or strain, associated with a given material when compacted.

Particle Design and drug Formulation:
1. Increase bio-availability of poorly soulbel molecules
2. Design formulations of sustained release
3. Develop less invasive to parenteral drug delivery

Biological applications
1.Cell Lysis
2. Preserving fragile molecules
3. Facilitating Downstream processing

Cost- consequence analysis