High-throughput screening: Beating the odds with informatics-driven chemistry

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How can an R& D department focus o­n compounds that are not just active, but also drugable'. Rather than rely o­n the wisdom of o­ne person, which was possible before the advent of high-throughput techniques, organizations must capture the chemical insights of everyone, something achievable o­nly with a virtual library. And they need tools to enable the efficient mining of that library and eliminate the randomness and data overload that has characterized the high-throughput process to date.  

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Author(s): 
Peter Hecht, Senior VP Discovery Research Operations, Tripos Inc, USA
Journal: 
Current Drug Discovery& ;January 2002
Copyright: 
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