Enteric Film Coating of Soft Gelatin Capsules

The formulation of drugs into soft gelatin capsules has gained popularity throughout the past decade due to the many advantages of this dosage form. The bioavailability of hydrophobic drugs can be significantly increased when formulated into soft gelatin capsules.1,2 Many problems associated with tableting, including poor compaction and lack of content or weight uniformity, can be eliminated when a drug is incorporated into this dosage form.3 Improved stability of drugs that are highly susceptible to oxidation can be achieved when formulated into a soft gelatin capsule.

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Author(s): 
Linda A. Felton,and James W. McGinity
Journal: 
Drug Delivery Technology, Vol 3 No 6 · September 2003 .