Drug Development Articles

Drug Development related full text articles from Pharmaceutical Journals

Closer to Transparency

To be sure, the road to clinical trials transparency is paved with good intentions—from the architects of http://www.clinicaltrials.gov//, to the sponsors, to the "external" stakeholders. But this road is proving to be a difficult one to travel.

Author(s): 
Lisa Henderson
Journal: 
Applied Clinical Trials, Mar 1, 2009

Development and characterization of orodispersible tablets of famotidine containing a subliming agent

Purpose: The purpose of the present research was to the effect of camphor as a subliming agent on the mouth dissolving property of famotidine tablets.

Author(s): 
S Furtado*, R Deveswaran, S Bharath, BV Basavaraj, S Abraham and V Madhavan
Journal: 
Tropical Journal of Pharmaceutical Research, December 2008; 7(4): 1185-1189

Quality of Artesunate Tablets Sold in Pharmacies in Kumasi, Ghana

Purpose: The study was carried out to evaluate the quality of artesunate tablets sold in retail and wholesale pharmacies in Kumasi, Ghana. In particular, the study sought to ascertain the presence or otherwise of counterfeit artesunate tablets in Kumasi.

Author(s): 
K Ofori-Kwakye*, Y Asantewaa and O Gaye
Journal: 
Tropical Journal of Pharmaceutical Research, December 2008; 7(4): 1179-1184

Aspects of microbial quality of some milk products in Abuja Nigeria

Purpose: To assess the microbiological quality of some milk products in Abuja, Nigeria capital city; and the resistance of isolates to some broad spectrum antibiotics.

Author(s): 
J Okpalugo, K Ibrahim, KS Izebe, US Inyang
Journal: 
Tropical Journal of Pharmaceutical Research, December 2008; 7(4): 1169-1177

Antibacterial Interaction of Crude Methanol Extract of Garcinia kola Seed with Gatifloxacin

Purpose: Concurrent use of orthodox and herbal medicines is likely to precipitate an overall effect which may or may not be beneficial to the patient.

Author(s): 
KC Ofokansi, AN Mbanefo, MN Ofokansi, CO Esimone
Journal: 
Tropical Journal of Pharmaceutical Research, December 2008; 7(4): 1159-1165

Antimicrobial Activity of Flavonoids against Extended-Spectrum β-Lactamase (ESβL)-Producing Klebsiella pneumoniae

Purpose: In the present study, six flavonoids (5,7-dimethoxyflavanone-4’-O-β-D-glucopyranoside, 5,7-dimethoxyflavanone-4’-O-[2’’-O-(5’’’-O-trans-cinnamoyl)-β-D-apiofuranosyl]-β-D-glucopyranoside, naringenin-7-O-β-D-glucopyranoside, 5,7,3’-trihydroxy-flavanone-4’-O-β-D-glucopyranoside, rutin, and nicotiflorin) isolated from Galium fissurense, Viscum album ssp.

Author(s): 
B Özçelik, D Deliorman Orhan, S Özgen, F Ergun
Journal: 
Tropical Journal of Pharmaceutical Research, December 2008; 7(4): 1151-1157

In-vitro Antimicrobial and Antitumor Activities of Stevia Rebaudiana (Asteraceae) Leaf Extracts

Purpose: The purpose of the study is to evaluate the antimicrobial and antitumor activities of Stevia rebaudiana (Asteraceae) leaf extracts.

Author(s): 
Sathishkumar Jayaraman*, Muthu Saravanan Manoharan, Seethalakshmi Illanchezian
Journal: 
Tropical Journal of Pharmaceutical Research, December 2008; 7(4): 1143-1149

Effects of Cassia occidentalis aqueous leaf extract on biochemical markers of tissue damage in rats

Purpose: Among the Hausas of Northern Nigeria, it is claimed by local (traditional) healers that the infusion of C. occidentalis leaves is used as a cure for hepatitis.

Author(s): 
AA Nuhu and R Aliyu
Journal: 
Tropical Journal of Pharmaceutical Research, December 2008; 7(4): 1137-1142

Genotoxicity studies of dry extract of Boswellia serrata

Purpose: Boswellia serrata, a common medicinal plant, has multiple uses in traditional medicine and, in particular, for the treatment of inflammatory diseases. The plant and its extracts have been evaluated for a number of activities, namely, anti-inflammatory, analgesic, anti-arthritic and antipyretic.

Author(s): 
V Magesh, D Raman and KT Pudupalayam
Journal: 
Tropical Journal of Pharmaceutical Research, December 2008; 7(4): 1129-1135

Short-Term Outcome of Combined Corticosteriod and Local Anaestetic Therapy with Home-Based Exercıse Programme in Painful Shoulde

Purpose: The aim of this study was to evaluate the efficacy of combined local corticosteroid and anaestethic therapy with home exercise programme in the treatment of painful shoulder conditions.

Author(s): 
S Toker, V Kılınçoğlu, A Toker, E Gulcan, E Ertürer, L Sahin
Journal: 
Tropical Journal of Pharmaceutical Research, December 2008; 7(4): 1123-1127
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