Drug Development Articles

Drug Development related full text articles from Pharmaceutical Journals

Phytochemical Screening and Antioxidant Activities of Some Selected Medicinal Plants Used for Malaria Therapy in Southwestern

Purpose: Oxidative stress has been shown to play an important role in the development of anaemia in malaria. Indeed, increase in total antioxidant status has been shown to be important in recovery from malaria. The antioxidant activities of four medicinal plants traditionally used in the treatment of malaria in southwestern Nigeria were determined.

Author(s): 
GA Ayoola, HAB Coker, SA Adesegun, AA Adepoju-Bello, K Obaweya, EC Ezennia, TO Atangbayila
Journal: 
Tropical Journal of Pharmaceutical Research, September 2008; 7(3): 1019-1024

The Pattern of Sale and Use of Non-Steroidal Anti-Inflammatory Drugs in Rural and Urban Centres in Nigeria

Purpose: The widespread use of non-steroidal anti-inflammatory drugs (NSAID) has meant that the adverse effects of these relatively safe drugs have become increasingly prevalent. This work examines the pattern of sale and use of NSAIDs as to call for caution in cases of misuse that may lead to renal, gastrointestinal and cardiac damage in users.

Author(s): 
OS Awofisayo, OA Awofisayo, II Iferi and OE Akpan
Journal: 
Tropical Journal of Pharmaceutical Research, September 2008; 7(3): 1013-1018

Effect of acid treatment on the consolidation and plasto-elasticity of tapioca powder

Abstract Full-Text

Purpose: The effects of treating the tapioca (the fibrous residue obtained after up to 90% of the proportion of starch has been removed from the peeled and rasped roots of cassava tubers powder with dilute solutions of hydrochloric acid) in order to find an approach for rendering an otherwise poorly compressible material to a directly compressible powder.

Author(s): 
Florence E Eichie† and Roland S Okor
Journal: 
Trop J Pharm Res, June 2002; 1(1): 45-49

Snake bites in Nigeria: A study of the prevalence and treatment in Benin City

Abstract Full-Text

Purpose: Although snake bites occur frequently in Benin City, the prevalence has not been documented. This study was therefore done to determine the prevalence, morbidity, mortality, and the orthodox treatment of victims.

Author(s): 
Eric K. I. Omogbai†, Zuleikha A. M. Nworgu, Michael A. Imhafidon, Anwakang A. Ikpeme, David O. Ojo and Charles N. Nwako
Journal: 
Trop J Pharm Res, June 2002; 1(1): 39-44

Preliminary investigation into the use of Pleurotus tuber-regium powder as a tablet disintegrant

Abstract Full-Text

Author(s): 
Magnus A Iwuagwul , Anthony O Onyekweli
Journal: 
Trop J Pharm Res, June 2002; 1(1): 29-37

Aspects of microbial contamination of tablets dispensed in hospitals and community pharmacies in Benin City, Nigeria

Abstract Full-Text

Author(s): 
John O. Akerele† , Godwin C. Ukoh
Journal: 
Trop J Pharm Res, June 2002; 1(1): 23-28

Novel colorimetric assay of mefenamic acid using 4-amino-3,5-dinitrobenzoic acid (ADBA)

Abstract Full-Text

Purpose: To develop a novel colorimetric assay method for mefenamic acid capsules.

Method: The new method (aromatic ring derivatization technique) is based on a diazo coupling reaction using diazotized 4-amino-3,5-dinitrobenzoic acid (ADBA) as a chromogenic derivatizing reagent.

Author(s): 
SO Idowu, SC Tambo, AO Adegoke, AA Olaniyi
Journal: 
Trop J Pharm Res, June 2002; 1(1): 15-22

Experimental and modeling studies of mass transfer in microencapsulated cell systems

Abstract Full-Text

Author(s): 
Mattheus F. A. Goosen
Journal: 
Trop J Pharm Res, June 2002; 1(1): 3-14

An Overview of Pharmaceutical Validation and Process Controls in Drug Development.

Abstract Full Text

Author(s): 
Jatto E and Okhamafe AO pp 115-22
Journal: 
Tropical Journal of Pharmaceutical Research 2002; 1(2): 115-22

Reclosure Efficiency of Plastic Container Used for Multidose Packaging of Moisture Sensitive Aspirin Tablets.

Abstract Full Text

Author(s): 
Ibrahim MA and Inyagi IJ pp 111-4.
Journal: 
Tropical Journal of Pharmaceutical Research 2002; 1(2): 111-114
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