Drug Development Articles

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Purpose: Drug microparticles may be microencapsulated with water-insoluble polymers to obtain controlled release, which may be further determined by the particle distribution. The purpose of this study was to determine the drug release parameters needed for the theoretical prediction of the release profiles of single aspirin crystals and their microcapsules.

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Purpose: Ideal behaviour of mixtures of organic modifier and water is reflected by a linear relationship between refractive index and fraction of organic modifier in the mixture. This study was carried out to investigate dimethylformamide (DMF) as an organic modifier in hydrophobicity index (Rm) determination.

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Objective: To evaluate the involvement of community pharmacists in primary health care; determine extent of the pharmacists’ participation in curative and preventive services, as well as partially assess quality of the involvement.

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Purpose: Pharmaceutical care (PC) is still a theoretical statement in Nigeria and not operational. The goal of this study is to identify practice standards that can be effectively applied in the implementation of pharmaceutical care in Nigeria.

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Purpose: Dioscorea dumetorum (Pax) used in traditional medicine for the treatment of diabetes mellitus possesses hypoglycaemic effect. The present study investigates the effect of oral administration of the aqueous extract of the tuber on blood lipid and ketone levels in alloxan–induced diabetic rats.

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Purpose: Inappropriate prescribing has been identified in many health facilities in developing countries. The purpose of this study was to evaluate the prescribing practices in two health care facilities in Warri located in south-south geopolitical region of Nigeria and identify factors influencing the practices.

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Purpose: To investigate a possible effect of chloroquine on urinary excretion of cloxacillin when chloroquine is administered concurrently with ampicillin-cloxacillin combination.

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Purpose: The aim of the present study is to investigate the physicochemical equivalence of eight brands of tablets containing sulfadoxine-pyrimethamine (antimalarial drug combination) sourced from different retail Pharmacy outlets in the Nigerian market.