Drug Development Articles

Abstract

Objective – Slugging is a pre-compression technique for the dry granulation of hydrolysable drugs (e.g. aspirin). The study was carried out to relate the slugging load to the hardness of the granules and the brittle fracture tendency of the final (recompressed) tablets.

For the past few decades, there has been a considerable research interest in the area of drug delivery using particulate delivery systems as carriers for small and large molecules. Particulate systems like nanoparticles have been used as a physical approach to alter and improve the pharmacokinetic and pharmacodynamic properties of various types of drug molecules.

Abstract

Purpose: The aim of the present study was to investigate antimicrobial activity of the various extracts of Stevia rebaudiana leaves.

Purpose: the aim of the present study was to investigate the efficacy of artemether-lumfantrine (Co-Artesiane®) suspension for the treatment of uncomplicated Plasmodium falciparum malaria in children (aged 6-59 months) in Kassala in eastern Sudan.

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Purpose: The problem of fake and counterfeit drugs is real and constitutes a major threat to the health and safety of the Nigerian population. A descriptive study was carried out to assess the methods of identification of counterfeit drugs by community pharmacists in Lagos State.

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Purpose: The study was carried out to assess the knowledge of community pharmacists who sell herbal/phytopharmaceutical formulations in pharmacy retail outlets.

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Purpose: The study was designed to evaluate the consistency of interpretation of results of interaction between ampicillin and ciprofloxacin against S. aureus and E. coli using three in vitro techniques.