Drug Development Articles
Antimicrobial Activity of Tamarindus indica Linn
Abstract
Compression, Mechanical and Release Properties of Chloroquine Phosphate Tablets containing corn and Trifoliate Yam Starches as B
Purpose: A study was made of the binding properties of trifoliate yam starch, obtained from Dioscorea dumetorum (Pax), in chloroquine phosphate tablet formulations in comparison with official corn starch.
Effect of Solvent Type and Drying Method on Protein Retention in Chitosan-Alginate Microcapsules
Purpose: The effect of solvent used in dissolving chitosan (membrane material) and the microcapsule drying method used, on protein retention in chitosan-alginate microcapsules were studied since these factors affect the physicochemical characteristics of the coating membrane.
In vitro Antimicrobial Activity of the Extract of Mitracarpus scaber Leaves Formulated as Syrup
Abstract
Purpose: To formulate the crude extract of the leaves of Mitracarpus scarber “Zucc” as a syrup.
Effects of Coadministration of Extract of Carica papaya Linn (family Cariaceae) on Activity of Two Oral Hypoglycemic Agents
Abstract
Purpose: To investigate the interacting effects of co-administration of Carica papaya leaf extract on the hypoglycemic activity of metformin and glimepiride in an animal model.
Evaluation of Pharmaceutical and Microbial Qualities of Some Herbal Medicinal Products in South Western Nigeria
Abstract
Purpose: The aim of the present study was to investigate the pharmaceutical and microbial qualities of 21 different (of various dosage forms) Herbal Medicinal Products (HMPs) sourced from some traditional medicine sales outlets and retail pharmacy outlets in south western Nigeria.
Formulation of Sodium Alginate Nanospheres Containing Amphotericin B for the Treatment of Systemic Candidiasis
Abstract
Purpose: The aim of this work was to formulate sodium alginate nanospheres of amphotericin B by controlled gellification method and to evaluate the role of the nanospheres as a “passive carrier” in targeted antifungal therapy.
A Comparative Evaluation of the Flow and Compaction Characteristics of a-Cellulose obtained from Waste Paper
Abstract
Purpose: Alpha-cellulose obtained as pulp from fibrous plant materials has found use in the pharmaceutical industry as a disintegrant and direct compression diluent. The aim of this study was to evaluate the suitability of α-cellulose obtained from waste paper as a direct compression excipient.
Modified Transdermal Technologies: Breaking the Barriers of Drug Permeation via the Skin
Transdermal drug technology specialists are continuing to search for new methods that can effectively and painlessly deliver larger molecules in therapeutic quantities to overcome the difficulties associated with the oral route, namely poor bioavailability due to hepatic metabolism (first pass) and the tendency to produce rapid blood level spikes (both high and low).
Evaluation of Phytochemical Constituents, Antibacterial Activities and Effect of Exudate of Pycanthus Angolensis Weld Warb (Myri
Purpose: A 1: 1: 2 mixture of exudates of Anchomonas difformis, Cyrtrospherma senegalense and Pycanthus angolensis is claimed to be used for the treatment of corneal ulcers.
