Soyabean powder as a novel diluent in tablet formulation of simvastatin

The present research paper introduces soyabean nuggets powder, as a novel excipient with nutraceutical value for tablets containing cholesterol lowering drug, simvastatin. Experiments were carried out to evaluate the suitability of soyabean nuggets powder as a diluent by incorporating in tablet formulation of simvastatin. The formulation was compared with the marketed product to determine its relative efficacy. Soyabean nuggets powder was found to be a promising diluent for tablets for both pharmaceutical and nutraceutical purposes. Simavastatin soya tablet showed acceptable pharmacotechnical properties and assay requirement. Keywords: In vitro drug release, novel excipient, powder characteristics, simvastatin, soyabean nuggets
Journal: 
Indian Journal of Pharmaceutical Sciences July-August 2010