General Principles Of Pharmacology

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This is pharmacology related free e-book availble online on Pharmaceutical encyclopedia  written by Prof.A.N.Nagappa

Chapter 1

  1. Introduction:Pharmacology and its Branches
  2. Passive Diffusion
  3. Facilitated Diffusion
  4. Active Transport
  5. Pinocytosis
  6. How do the molecules cross the cell membrane?
  7. Drug Distribution And Other Factors
  8. Passage of drug into the CNS
  9. Passage of drug into the Placenta
  10. Drug Dilution in Body Water
  11. Sites of Drug Binding and its Effect on Drug Distribution
  12. Drug metabolism: some definitions and explanatory notes their glomerular filtration
  13. Drug Transformation and Clinical Considerations
  14. Individual Differences
  15. Age and Sex Differences
  16. Drug Transformation and Drug-Drug Interactions
  17. Drug Transformation of Endogenous Compounds
  18. Drug Transformation in Diseases and Drug Metabolism
  19. Drug Transformation and Toxic Products

Chapter 2

  1. Pharmacodynamics
  2. Cells of the CNS
  3. Neurotransmitters
  4. The Synapse
  5. Drug-Receptor Affinity: Agonists and Antagonists
  6. Agonistic Mechanisms
  7. Antagonistic Mechanisms
  8. Sites of Drug Action: Drugs and Receptors
  9. Disease Processes
  10. Concept of specific drug receptors
  11. Types of Receptors
  12. Drug Therapy
  13. Binding and Response
  14. Molecular Aspects of Binding
  15. Measurement of Effect
  16. Analysis of Effect
  17. Occupation Theories
  18. Responses in the Patient
  19. Responses in a Population
  20. Therapeutic Index

Chapter 3

  1. Pharmacokinetics
  2. Three Basic Concepts
  3. First Order Model
  4. Multiple Dose Kinetics
  5. Renal Extraction Ratio
  6. Drug Excretion:Mechanisms of Renal Excretion