Latest approval in pharmacy
Date of Approval: September 25, 2009
Company: Centocor Ortho Biotech Inc.
Treatment for: Psoriasis
Stelara (ustekinumab) is a human monoclonal antibody for the treatment of moderate to severe plaque psoriasis.
Psoriasis is a common skin condition that causes skin redness and irritation. Most persons with psoriasis have thick, red skin with flaky, silver-white patches called scales.
Psoriasis seems to be an inherited disorder. That means it is passed down through families. Doctors think it probably occurs when the body's immune system mistakes healthy cells for dangerous substances.
Skin cells grow deep in the skin and normally rise to the surface about once a month. In persons with psoriasis, this process is too fast and dead skin cells build up on the skin's surface.
Psoriasis may affect any or all parts of the skin. There are five types of psoriasis.
•Plaque -- Thick, red patches of skin are covered by flaky, silver-white scales. This is the most common type of psoriasis.
In general, psoriasis may be severe in persons who have a weakened immune system. This may include persons who have:
•Autoimmune disorders (such as rheumatoid arthritis)
Up to 30% of people with psoriasis may also have arthritis, a condition known as psoriatic arthritis. Psoriasis may also affect the nails. About 10% of people with psoriasis have visible changes only in the nails.
Persons with psoriasis have irritated patches of skin. The redness is most often seen on the elbows, knees, and trunk, but can appear anywhere on the body. For example, there may be flaky patches on the scalp.
The skin patches or dots may be:
•Pink-red in color (like the color of salmon)
•Dry and covered with silver, flaky skin (scales)
•Raised and thick