Abstract:

Skin is an important site of drug application for both local and systemic effects. For transdermal delivery of drugs, stratum corneum (SC) is the main barrier for permeation of drug. So to circumvent the SC, different approaches of penetration enhancement are used. Carriers/vesicles such as liposomes, niosomes, ethosomes, microemulsions, complexes, prodrugs provide better alternative method to enhance permeation of drugs through skin.