Natural Excipients
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CHARCOAL ACTIVATED
Definition:
Activated charcoal is the residue from the destructive distillation of various organic materials, treated to increase its adsorptive power. It is mainly obtained from sawdust, cellulose residues and coconut shells.
Uses:
1. Charcoal is employed either in powder, granules, tablets and sometimes with light kaolin or as charcoal biscuits to adsorb gases in treatment of flatulence.
2. It also used as purifying and decolourising agent.
CARDAMOM OIL
Definition:
It is the volatile oil distilled from the seed of elettaria cardamomum muton, family zinzibereaceae).
Uses
1. Aromatic, carminative and stimulant, flavouring agent. Cardamom oil finds main application in flavouring of processed foods.
2. It is also used in certain liquid products such as cordials, bitters and liquors and occasionally in perfumery.
CARNAUBA WAX
Definition:
Carnauba wax is obtained from leaves of copernicia cerifera (fam-palmae)
Uses
1. It is used as tablet coating agent (10% w/v ) aqueous emulsion.
2. It is wild used in cosmetics mainly in lip balms, solid brilliantine (5% by wt), stick eye shadow, sunscreen sticks and in phytocosmetics as a replacement for bees wax.
3. Its used in alone or in combination with hydroxyl propy1 cellulose, alginate and stearyl alcohol to produce sustained release solid dosage formulations.
4. Its used for preparation of confictionary and in formulation of cosmetics.
Castor oil
Definition
Castor oil is the fixed oil obtained by the cold expression of the seed of ricinus communis. Family – euphorbiaceace.
Uses.
1. Castrol oil is widely used in cosmetics, food products and pharmaceutical formulations in cosmetics its employed as an emollient in preparations of lipsticks and as the performed hair oil and hair fixer.
2. Castor is the cathartic.
3. Its also used for lubrication commercially.
4. The fatty acids like ricinolic, heptaldehyde and undecenoic and commercially prepared for castor oil.
5. Fungicide undecylenic acid is prepared from the castor oil.
Castor cake is used as a source of enzyme lipase.
Referenceses same as from previous blogs.


Comments
sirisha
Wed, 09/30/2009 - 04:33
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dear kranthi,.. Great
dear kranthi,..
Great Explanation..Instead definition, i think Biological source is apt for the data you provided..
Sirisha Pingali
http://www.pharmainfo.net/sirisha
kranthikumar
Wed, 09/30/2009 - 14:55
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I have mentioned both.
Dear Sirisha,
Thanks for your view, I have provided both of them.
Regards Kranthi http://www.pharmainfo.net/kranthikumar/biography
nikhilkarani
Wed, 09/30/2009 - 08:43
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Dear Kranthi, good
Dear Kranthi,
good explanation.
But, i would like to tell that:
activated charcoal is no longer used in any dosage forms as mentioned by you in treatment of flatulence.
also, Carnauba wax is avoided in use as 10%w/v for tablet coating.
you have many better, new synthetic coating agents available.
kranthikumar
Wed, 09/30/2009 - 14:54
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Thank you.
Dear Nikhil,
This is blogs are not to say its a new invention or now in use but meant to remind that natural excpients can be used in many ways. Its like high lighting the natural sources .
Hope you understood!!!
Regards Kranthi http://www.pharmainfo.net/kranthikumar/biography
nikhilkarani
Thu, 10/01/2009 - 05:41
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Dear Kranthi, The only reason
Dear Kranthi,
The only reason for the above natural excipients being not in use are some of their disadvantages that lead to development of synthetic counterparts to replace them.
For eg.Use of Carnauba wax in coating:
First of all there are contamination issues with C.wax (it being natural ingd).
secondly, the effeciency of coating with C.wax is poor.
the process time required is also high.
&, MOST IMPORTANTLY, cleaning after wax coating is difficult and may give rise to problems in Cleaning validation (during scale up).
ALSO, C.wax sometimes gives issue in scale-up procedures, which may make coating difficult.
There are many such examples.
rajanraju
Wed, 09/30/2009 - 15:27
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Good information.
Dear Kranthi,
Good, its always good to depend on the natural sources than some artificial stuff. Keep doing this .
Regards
Rajan raju
" KINDLERS "
www.pharmainfo.net/rajaraju
ks kumar upadhyayula
Thu, 10/01/2009 - 19:09
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Good Approach
Dear Kranthi,
Very nice approach in presenting the blog,all the important aspects are covered that a pharmacist is ought to know for his knowledge.Keep it up and hope to see you at a still more rapid pace.
http://www.pharmainfo.net/ks-kumar-upadhyayula
zarrinfaria
Tue, 10/06/2009 - 08:29
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Dear Kranthi... Good
Dear Kranthi...
Good stuff...are these natural excipients compatible with synthetic API
Regards,
Faria Zarrin
Team: BLOGBUSTERS
My Page :
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