In vitro anthelmintic property of various seed oils against Pheritima posthuma

Seed oils of Gynandropsis gynandra, Impatiens balsamina, Celastrus paniculata, Embelia ribes and Mucuna pruriens were investigated for their anthelmintic property against Pheritima posthuma . Three concentrations (10, 50 and 100 mg/ml) of each oil were studied in a bioassay, which involved the determination of time of paralysis and time of death of the worm. All the oils exhibited moderate to significant anthelmintic activity. Embelia ribes showed the best anthelmintic activity in both the parameters. Piperazine citrate (10 mg/ml) was included in the assay as standard reference drug.

Author(s): 
SS Jalalpure, KR Alagawadi, CS Mahajanashetti, BN Shah, Salahuddin, Vijay Singh, JK Patil
Journal: 
Indian Journal of Pharmaceutical Sciences ,Year : 2007 | Volume : 69 | Issue : 1 | Page : 158-160