Patient counselling for antibiotics: Aminoglycosides

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Aminoglycosides

Information for pharmacist:

  1. Must be given for the full course of treatment.
  2. It works best when a certain amount of drug is present in blood or urine, i.e. doses must be given on a regular schedule.
  3. Doses must be calculated based on body weight and must be determined by the medical practitioner. Any corrections in dose must be made if necessary and the practitioner must be notified.

Dosing for drugs:

  • Amikacin (for all dosage forms)
    • Adults and children: every 8 or 12 hours for 7 to 10 days
    • New borns: every 12 hours for 7 to 10 days
    • Premature babies: every 18 to 24 hours for 7 to 10 days
  • Gentamicin (for all dosage forms)
    • Adults and children: every 8 hours for 7 to 10 days or more
    • New borns: every 8 to 16 hours for 7 to 10 days or more
    • Premature babies: every 12 to 24 hours for 7 to 10 days or more
  • Tobramycin (for all dosage forms)
    • Adults and adolescents: every 6 to 8 hours for 7 to 10 days or more
    • Older infants and children: every 6 to 16 hours
    • Premature and full term new borns: every 12 to 24 hours
  • Streptomycin (for all dosage forms)
    • Tretment of TB
      • Adults and adolescents: 1 g injected into muscle once everyday, it wil be reduced to 2 to 3 times a week after some time
      • Children: dose based on body weight and injected into muscle once everyday
    • Treatment of bacterial infections
      • Adults and adolescents: 250 mg to 1 g injected into muscle every 6 to 12 hours
      • Children: dose based on body weight and injected into muscle every 6 to 12 hours

Information for patient:

  1. Follow doctor's advice on directions for use and dosing intervals strictly.
  2. Dose change (if any) must be done after consultation with the physician.
  3. Check with physician immediately if there is a problem with hearing, experience unsteadiness, dizziness, numbness or muscle twitching.
  4. Also consult with physician if even after completing the course, the side effects continue or get worse.

Reference:

1) Advice for the patient: Drug information in lay language; USP DI; 1995,15th edition; pg: 202-204 [access date: 16thSeptember, 2010]

2) http://www.aafp.org/afp/981115ap/gonzalez.html [access date: 16th September, 2010]

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About the Author

Niklesh Rao V's picture
Author: Niklesh Rao V

Comments

P.V.ABHIGNA's picture

Niklesh, In what cases do premature babies receive treatment with these drugs.Is it not harmful to use them for about 7 days in them. Regards,

ABHIGNA.P.V.

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