There are two basic pharmacokinetic processes on which the pharmacological response of a drug is dependent. Those are namely, drug absorption and drug disposition. On the other hand, the rate of elimination decides the duration and intensity of action of a drug.
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Drug metabolism and pharmacokinetics (DMPK) plays significant roles in the discovery and developments of drugs. Considering the lack of academic scientists in the field of DMPK in India, the main goals of the Symposium are:
The concept of drug design is neither new nor the discussion would involve any novel concepts. But, since the concepts and knowledge of drug design is an interesting field, I was tempted to discuss about this area, especially important for a medicinal chemist. The drug design is generally considered to be rational, since it takes into account an intensive knowledge about the molecular target on which a drug acts. Through this process of drug design, several new leads can be obtained which might later on prove to useful drug molecules.
Computational knowledge describes the use of computational power and software in predicting certain properties and characteristics of a compound or compounds, before opting for synthesis.