Pharmacogenomics

TNVD PAVAN KUMAR's picture
By TNVD PAVAN KUMAR - 10/31/2009
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Pharmacogenomics is the branch of pharmacology which deals with the influence of genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with a drug's efficacy or toxicity. By doing so, pharmacogenomics aims to develop rational means to optimise drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Such approaches promise the advent of "personalized medicine"; in which drugs and drug combinations are optimized for each individual's unique genetic makeup.

Pharmacogenomics is the whole genome application of pharmacogenetics, which examines the single gene interactions with drugs.

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Ayush A. Singhal's picture

Can you suggest some of the

Submitted by Ayush A. Singhal on Fri, 11/20/2009 - 17:23.
3

Can you suggest some of the means where by pharmacogenomics will help us in fighting with dug resistance associated with anti virals and anti biotic?

Ayush A. Singhal
RPCP, CHANGA
GUJARAT
http://www.pharmainfo.net/ayushsinghal

deepika garikipati's picture

good

Submitted by deepika garikipati on Fri, 11/20/2009 - 12:45.
3

nice ppt

ABHERI DAS SARMA's picture

Nice presentation

Submitted by ABHERI DAS SARMA on Fri, 11/20/2009 - 05:15.
4

How does interethnic difference influence pharmcogenomics?

ABHERI DAS SARMA
http://www.pharmainfo.net/abherids86

Dixon Thomas's picture

Dear Pavan Hope

Submitted by Dixon Thomas on Thu, 11/19/2009 - 12:18.
4

Dear Pavan
Hope pharmacogenomics takes its place in medical science and come to regular practise. Then Pharmacist shall be necessary in clinical side to practice it along with doctors right. Could you explain the would be role of clinical pharmacist then?

Mr. Dixon Thomas, M. Pharm, M. S., RPh
http://www.pharmainfo.net/pharmacistdixon

komal nikam's picture

Hollo, please discuss

Submitted by komal nikam on Wed, 11/18/2009 - 14:53.
3

Hollo,
please discuss relation between pharmacogenomics & statistic ? how it will help in pharmacogenomics studies?

Komal Nikam
http://www.pharmainfo.net/komal-nikam

komal nikam's picture

Hy, How one can avoid diff.

Submitted by komal nikam on Wed, 11/18/2009 - 14:50.
3

Hy,

How one can avoid diff. barriers with the help of pharmacogenomics?

Komal Nikam
http://www.pharmainfo.net/komal-nikam

Pankaj Patel's picture

abt cost of drug

Submitted by Pankaj Patel on Wed, 11/18/2009 - 13:42.
3

as pharmacogenomics- study related to drug response in individual.
what are the different screening test available to check susceptibility of drug with individual?
Tell about cost factor and risk-benefit ratio for these approach.

http://www.pharmainfo.net/pankajpatel

Khushbu Hasmukh Patel's picture

1. What are the side effect

Submitted by Khushbu Hasmukh... on Wed, 11/18/2009 - 07:09.
3

1. What are the side effect of pharmacogenomic?
2. how mutaion effects pharmagenomics studies and what are the factors to be consider in dealing with mutation in pharmacogenomics?

K.H.Patel.
My profile link is
http://www.pharmainfo.net/khushbu-hasmukh-patel

Dr R S Prakasham's picture

question

Submitted by Dr R S Prakasham on Wed, 11/18/2009 - 03:29.
3

Is there any study on multigene related personalized medicine development? How the allelic genes respond to personalized medicine?

Hemangi Purarkar's picture

Hi Pavan

Submitted by Hemangi Purarkar on Tue, 11/17/2009 - 20:32.
3

Is there any Quality Control OR Quality Assurance methods available for the Pharmacogenomics?

Ritesh Bajaj 's picture

miRNA and there relationship in pharmacogenomics

Submitted by Ritesh Bajaj on Sun, 11/15/2009 - 16:55.
3

how do you relate the above topics and explain there interdependence.
please be more specific towards these aspects regarding pharmacogenomics.

T.Nithya's picture

proteogenetics

Submitted by T.Nithya on Sun, 11/15/2009 - 15:50.
2

hi
good presentation
i have a doubt
can u please explain what do u mean by proteogenetics

http://www.pharmainfo.net/nithya035

KINJAL B. RATHOD's picture

Query

Submitted by KINJAL B. RATHOD on Sun, 11/15/2009 - 10:43.
2

Hello,
nice PPts

how far indian people to have genetic profile ID card with them individualy??
with out it personalized mediccine concept is not possible, I thought so.

KINJAL B. RATHOD
http://www.pharmainfo.net/kinjal

Jithan Aukunuru's picture

statistics!

Submitted by Jithan Aukunuru on Sun, 11/15/2009 - 01:51.
3

Compare statistics vs pharmacogenomics in drug discovery.

Dr. T.E.G.K. Murthy's picture

Try to strenghen the information

Submitted by Dr. T.E.G.K. Murthy on Thu, 11/12/2009 - 08:38.
2

1. Is there any statuatory guidelines to conduct pharmacogenetic studies ?

2. How subjects are selected to conduct pharmacogenetic studies.

3. The experimental data generated from animals can be extra polated to human beings or not ?

scope of pharmacogenomics

Submitted by rakesh on Sat, 11/07/2009 - 16:37.
3

can you tell me the scope of pharmacogenomics

Noopur's picture

possible barriers in the pharmacogenomic studies?

Submitted by Noopur on Tue, 11/03/2009 - 18:15.
3

hi...
good presenatation.
can u tell me wat are the possible barriers in the pharmacogenomic studies?

noopur
http://www.pharmainfo.net/noopur-wani

raghavendra swamy's picture

AS, Mn SOD genes, and IBD

Submitted by raghavendra swamy on Tue, 11/03/2009 - 12:10.
2

Pavan, in your ppt i can see many abbreviations some of which i can't understand could you explain the following: AS, Mn SOD genes, and IBD.
Also explain about LOD score in detail.

http://www.pharmainfo.net/raghavendraswamy