Polymers In Drug Delivery
Conventional forms of drug delivery generally rely on tablets, eye drops, ointments and intravenous solutions. Recently, a number of novel drug delivery technologies have developed. These newer technological development include drug modification by chemical means, career based drug delivery and drug entrapment in polymeric matrices or within pumps that are placed in desired bodily compartments. These technical development in drug delivery/targeting approaches improve the efficacy of drug therapy thereby improve human health. Still there are many infectious and other deadly diseases are uncured due to the problem encountered by formulation scientists in drug delivery approaches. There is a strong need to develop a proper delivery system to achieve the complete therapeutic effects of the existing drug molecules. Use of polymeric materials in novel drug delivery approaches has attracted the scientists. Polymer chemists and chemical engineers, pharmaceutical scientists are engaged in bringing out design predictable, controlled delivery of bio active agents. When the drug is delivered to the site of action by using polymer based drug delivery approaches the safety and bio compatibility is questionable. The characterization of biocompatible polymers is more focused in the field of formulation development and drug delivery approaches etc. the biodegradable polymers have properties of degrading in biological fluids with progressive release of dissolved or dispersed drug. There is various novel drug delivery approaches are developed in the pipeline of polymer based drug delivery approaches. The bio-safety and biocompatibility are the important characteristics needed for the use of polymers in the field of pharmaceutical formulation and in novel drug delivery approaches. The present paper review is focused in the advances of biodegradable polymers based drug delivery approaches.
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