Pharmaceutical Packaging Articles

From a packaging perspective, the
themes of the 2001 Interphex show
held in March in Philadelphia were
easier operation, quicker changeover,
and product security. Nearly all categories
of equipment, containers, and materials
were well represented among the
approximately 900 exhibitors spread across
240,000 ft2 of floor space.
Flexible packaging
Bags used for the delivery of parenteral nutrition,
antibiotics, and specialty drugs andfilm is extruded as a tube in a controlled
environment so only Class 100 filtered air
touches the inside product-contact surface,
which then is protected throughout
packaging, distribution, and use on the
form–fill–seal equipment (M312 film, Cryovac
North America, Duncan, SC).

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Managing the cold chain not only keeps products at the proper temperatures, but it also can increase supply chain efficiency and reduce costs. A close-up look at the cold-chain operations of Mayne Pharma (Melbourne, Australia, www.maynegroup.com) illustrates these benefits. Raymond Jenkins, global demand and logistics manager at Mayne Pharma’s regional head office in New Jersey, cut shipping time from the company’s manufacturing site in Australia to Dallas, Texas, from 10 days to less than 72 hours, saving his company $300,000 per year.Drawing on 20 years of materials management experience, Jenkins did his homework and discovered that goods were sitting idle in customs waiting for import clearance. So he created a shipment template harmonized to the tariff schedule.

BR> Advances in the HPLC Column Packing Design
 
Even though HPLC column technology is considered to be somewhat mature, new developments continue. Improvements in packing-material design, bonded-phase chemistry, column construction and formats have occurred. Users now have a better understanding of the advantages and limitations of silicabased materials and do not attempt to use them under conditions that may shorten their lifetime or decrease their performance. In addition, new phases have extended operating pH ranges (high and low) providing more versatility. In this article, I will update developments in packing morphology and particle design. Instead of trying to cover the entire domain of HPLC column development, I will focus on a few key areas.
 
Improvements in Porous Packings:
 
Porous packings have been in favour throughout the history of HPLC.

BR> The transformation of the healthcare industry is moving the pharmaceutical packaging industry into the spotlight as never before. It is an obsolete notion to view packaging as an afterthought in the development of pharmaceutical products. Various trends are making pharmaceutical packaging more complex, the increase in combination products being one of the most dominant. With combination products, packaging moves beyond being a mere container to become an integral part of the product, blurring the line between medical device and pharmaceutical formulation. A prime example of this trend is prefillable syringes, one of the fastest growing product categories because of their of ease-of-use and drug response-time advantages.



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