Fundamentals for Controlled Release Systems
Recently, Controlled Release (CR) systems have become a very useful tool in medical practice, offering a wide range of actual and perceived advantages to the patients. CR Systems are designed to maintain constant therapeutic plasma concentration of the drug within the therapeutic range of drug over prolonged periods. These delivery systems offer numerous advantages in comparison to conventional dosage forms, which include fewer doses per day or week and reduce in adverse effects
The present presentation includes
Classification of Controlled Release System based on fabrication techniques.
Mechanism of controlled drug release using polymers.
Polymer used for controlled drug release.
Overview of application of mathematical models for controlled release products.
Evaluation of CR product
Key words: Controlled Release (CR), Dissolution controlled, Diffusion controlled, Osmotically controlled, Mathematical models.
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