Rohdococcus bacteria: A new antibiotic agent in Pharmaceutical field

Researchers noticed that Rhodococcus bacteria have inherent antibiotic activities when it is introduced in strain conditions and with improper nutrient conditions.

The researchers first found out that the Rhodococcus bacteria have hidden properties when they were sequencing its genome. When researchers have compared those genomes with other bacteria, they found that Rhodococcus bacteria share many of genomes which help in the productions of antibiotics.

During the furthers studies the way towards Rhodococcus bacteria, they have found that antibiotic generated is of similar to kind of streptomycin bacteria, but when the team, lead by Kazuhiko kurosawa, they have studied the pattern of bacterial antibiotic generation, they have found that, that it may have arsenic like chemical which lead to put this bacteria in antibiotic generating species.

Team further carried out series of practicals and concluded that this antibiotic generates only in the environmental strain and insufficient or altered nutrient supply. Then the team grew the Rhodococcus bacteria in the Streptomycin bacterial species.

Under such conditions Rhodococcus bacteria killed the all competitive bacteria inside test-tube. Team has isolated the antibiotic and named Rhodostreptomycin. They tried that antibiotics with other pathogens and antibiotic successfully killed them. Such antibiotic may also helpful to destroy those pathogens which survive even in harsh conditions, like H. pylori, which can withstand in the highly acidic conditions.

Structure of Rhodostreptomycin molecule is amino glycride antibiotics with two ring structures that have been not found out in any antibiotic yet. Production of this antibiotic is not yet understand as the fact that, the normal Rhodococcus bacteria does not have such genomes which produce the antibiotics, thus it may happen that in the adverse conditions bacteria may borrowed DNA from the competitive bacteria.