<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><ref-type>34</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Gendle Ravindra</style></author><author><style face="normal" font="default" size="100%">Kaushik Basant</style></author><author><style face="normal" font="default" size="100%">Verma Laxmi</style></author><author><style face="normal" font="default" size="100%">Dewangan Pramod</style></author><author><style face="normal" font="default" size="100%">Verma Shekhar</style></author><author><style face="normal" font="default" size="100%">Namdeo Kamta Prasad#</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">PARAMETERS REQUIERED FOR SUSTAINED RELEASE DRUG DELIVERY SYSTEM</style></title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Extended release</style></keyword><keyword><style  face="normal" font="default" size="100%">Hydroxy propyl methyl cellulose</style></keyword><keyword><style  face="normal" font="default" size="100%">sustained release</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2009</style></year></dates><abstract><style face="normal" font="default" size="100%">Oral drug delivery is the largest and the oldest segment of the total drug delivery market. It is the fastest growing and most preferred route for drug administration. Use of different release retardant for oral sustained release of drugs is a common practice in the pharmaceutical industry. In this study discusses formulation and manufacturing variables affecting the design and performance of the extended-release product by using selected practical examples.Optimal therapy of a disease requires an efficient delivery of active drugs to the tissues, organs that need treatment. Very often doses far in excess to those required in the cells have to be administered in order to achieve the necessary therapeutically effective concentration. This unfortunately may lead to undesirable, toxicological and immunological effects in non-target tissue. A controlled release dosage forms leads to better management of the acute or chronic disease condition.</style></abstract></record></records></xml>