Attempt to make PLAGIARISM practically understand!

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Dear Readers, You are already enlightened with theory behind the PLAGIARISM with the beautiful blogs kept by our fellow leaders. Here is an attempt to bring the practical way of applying that knowledge to give further clarity to the readers/ learners.Let us see the ways of presenting data on our well known ASPIRIN!

Wong Way of presenting the data:

Committed Plagiarism

RIGHT way of presenting the data:

NO Plagiarism

Inhibition of COX-2 enzyme is the secret behind antipyretic, analgesic and antiinflammatory actions of NSAIDs. Complications of NSAID therapy like gastrointestinal (GI) bleeding and renal toxicity are due to inhibition of COX-1.

The antipyretic, analgesic, and antiinflammatory actions of NSAIDs are related to their ability to inhibit COX-2. Side effects such as gastrointestinal (GI) bleeding and renal toxicity are a result of the inhibition of COX-1 and are well known complications of NSAID therapy.1

Do you know! Aspirin should not be given to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox. Aspirin can cause a serious and sometimes fatal condition called Reye's syndrome in children 

Aspirin should not be given to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox. Aspirin can cause a serious and sometimes fatal condition called Reye's syndrome in children.2 

There will be potential Attenuation of the Anti-Platelet Effect of Aspirin upon Concomitant Use of Ibuprofen and Aspirin

Concomitant Use of Ibuprofen and Aspirin results in Potential Attenuation of the Anti-Platelet Effect of Aspirin3

Amazing fact, the prolonged administration of a typical regimen of delayed-release diclofenac (twice daily) did not inhibit the antiplatelet effect of enteric-coated aspirin.

“The prolonged administration of a typical regimen of delayed-release diclofenac (twice daily) did not inhibit the antiplatelet effect of enteric-coated aspirin”4 as reported b Catella-Lawson et al.

Naproxen interferes with the inhibitory effect of aspirin on platelet COX-1 activity and function resulting in the undermine sustained inhibition of platelet COX-1 that is necessary for aspirin’s cardioprotective effects.

In 2005 Capone ML et al reported that “Naproxen interfered with the inhibitory effect of aspirin on platelet COX-1 activity and function. This pharmacodynamic interaction might undermine the sustained inhibition of platelet COX-1 that is necessary for aspirin’s cardioprotective effects”.5 

Good news to Breast Cancer patients: Aspirin can significantly reduce the risk of cancer spread and death for women who have been treated for early stage breast cancer.

"This is the first study to find that aspirin can significantly reduce the risk of cancer spread and death for women who have been treated for early stage breast cancer, " said Dr. Michelle Holmes of Harvard Medical School, who led the study published in the Journal of Clinical Oncology.6

Aspirin structure

Aspirin Structure

 


Source: www.wikipedia.com

 

The below write ups will surely sounds good in the concept behind PLAGIARISM… Have A Look!

We are OPEN to learn from you all . Please comment!.

 

References:

1. Goodman’s &Gilman’s The Pharmaceutical Basis of Therapeutics, 5th ed. New York, Mcgraw-Hill,1996: 617-43.. (Accessed February 18th 2010)

2. http://www.drugs.com/aspirin.html . (Accessed February 18th 2010)

3. FDA - Postmarket DrugSafety Information for Patients and Providers . (Accessed February 18th 2010)

4. Catella-Lawson et al. Cyclooxygenase inhibitors and the antiplatelet effects of aspirin. NEJM; Dec 2001; 345: 1809-1817.. (Accessed February 18th 2010)

5. Capone ML et al. Pharmacodynamic interaction of naproxen with low-dose aspirin in . (Accessed February 18th 2010)

healthy subjects. J Am Coll Cardiol 2005; 45: 1302-1303. . (Accessed February 18th 2010)

6. http://www.msnbc.msn.com/id/35426947/ns/health-cancer/. (Accessed February 18th 2010)

This blog-post does not contain plagiarized material

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