Dispensing and Hospital Pharmacy

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While coming to Dispensing and Hospital pharmacy, I could find diversified
range of questions from the past question papers... Here are some of them

I) Write a note on the following (4 or 6 marks)

1. General principles of dispensing

2. Importance of bioavailability in dispensing.

3. Prescription and its parts.

4. Care in handling a prescription.

5. Errors in dispensing

6. Information required on labels of dispensed preparations and its importance.

7. Posology

8. Unit dose dispensing

9. Proof strength

10. Douches

11. Linctuses

12. Effervescent granules

13. Displacement value and its significance.

14. Preparation of creams.

15. Measures to retard creaming in emulsions

16. What difficulty could be anticipated in dispensing of hydrophobic insoluble
drug powder in a mixture?

17. Preservation of ophthalmic preparations.

18. Prepacking

19. Storage of biological products belonging to Schedule C and C1.

20. OTC drugs.

21. Potent medicament.

II) Differentiate between the following: (4 or 6 or 8 marks)

1. Pastes and Jellies

2. o/w and w/o emulsion

3. Liniment and lotion

4. Ointment, cream and paste

5. Suppository and pessary.

6. Elixir and syrup

7. Paste and Jelly

8. Eye drop and Ear drops

III) Following are the questions which are generally asked for
8 or 10 marks….

1. Classify mixtures with examples. Describe the method of preparation and labeling
of indiffusable mixtures.

2. Write the general dispensing procedure.

3. What are soft gelatin capsules? Discuss about soft capsules as a unit dosage

4. Different tests for finding out the type of an emulsion.

5. What are the characteristics of ideal ointment bases? Discuss different ointment
bases and their advantages and disadvantages

6. What are the characteristics of ideal suppository bases? Discuss different
suppository bases and their advantages and disadvantages

7. Formulation and preparation of elixirs.

8. Discuss the formula and method of preparation of “Mandl’s Paint”.

9. Different methods to calculate the dose of children.

10. Explain the organization of a hospital

11. Define hospital pharmacy. Discuss the functions, duties and responsibilities
of hospital pharmacists.

12. What are the facilities required in a hospital regarding administration,
location and equipment.

13. Duties of Pharmacy and therapeutic committee.

14. Discuss the objectives and functions of Central Sterile supply services
and its organization.

15. Write notes on Inpatient and Outpatient dispensing unit.

16. How is inventory control done in a hospital pharmacy unit

17. Discuss the procedures adopted in purchase of drugs.

18. How is drug information centre organized?

19. Current status of hospital pharmacy in India. What changes are anticipated?

20. Role of pharmacist in community health care.

IV) Some essay questions which are asked for 16 marks

1. Discuss physical, chemical and therapeutic incompatibilities.

2. Classify powders. Give principles, procedures and labels for powders containing
liquids, eutectic powders and powders containing potent substances.

3. What are emulsions? Discuss the pharmaceutical applications of emulsions.
Enumerate the factors influencing the stability of emulsions and its preservation.
Write a note on different emulsifying agents.

V) Problematic questions: (2 or 4 or 6 marks)

1. How will you prepare 500 ml of 0.01 N Hcl from 10 N Hcl

2. How do you prepare 500 ml of 50 % alcohol with the 80 % alcohol and 30 %

3. How do you prepare 45% alcohol from 95% and 30 % alcohol.

4. The adult dose of a drug is 600 mg. What is the dose for the same for a 2
year old child?

5. How do you prepare 100 ml of a solution of Potassium permanganate such that
when 5 ml of this solution is diluted to 50 ml it gives a 1 in 10000 solution?

6. Supply six suppositories each weighing 15 grains and containing 40 % zinc
oxide (D.V of ZnO is 5.0)

7. Calculate for the preparation of 6 Bismuth subgallate suppositories, using
cocoa butter base in a 1 gm mold. The displacement value of Bismuth subgallate
is 2.7 and each suppository must contain 300 mg of Bismuth subgallate.

8. Give the formulae for preparing 60 ml of 2 % Isotonic solution of cocaine
hydrochloride using sodium chloride. (F.P of Cocain Hcl and NaCl is 0.09 and

9. Calculate the percentage of anhydrous dextrose required to render a 1% solution
of ephedrine hydrochloride iso- osmotic with body fluids. (NaCl equivalent of
1 % ephedrine hydrochloride= 0.30, NaCl equivalent of 1 % dextrose = 0.18)

10. Prepare 30 ml of isotonic 0.1% solution of dexamethasone sodium phosphate
0.9 % Sodium Chloride solution has a depression in freezing point of 0.52 and
0.52 % dexamethasone sodium phosphate has a depression of 0.05.

VI) How will you dispense the following prescriptions? (4 or 6

Phenacitin- 3 g

Caffeine- 1 g

syrup of orange- 12 ml

water upto 90 ml

Fiat mistura. Label: Take a tablespoonful with milk when pain
is severe.

Codeine phosphate- 6 mg

Make powder. Send 10 powders.

Signa: Take one when cough is severe.

Hyoscine hydrobromide- 0.4 mg

Prepare a powder. Send 12 powders; Label: Take one twice a day.

Quinine sulphate- 0.8 g

Dil Sulphuric acid- 2ml

Potassium iodide- 5 gm

Water upto 100ml. Prepare a mixture. Label: Take a tablespoonful
every 4 hours.

Liquid Ferric Chloride- 4ml

sodium Benzoate- 8g

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water- 180 ml

Label: Take a tablespoonful twice a day.

Cetrimide- 0.5 g

Cetosteryl alcohol- 5 g

Soft paraffin- 5g

Liquid paraffin- 15 g

Purified water- 25 gm

Label: Antiseptic cream.

Triethanol amine- 1ml

Oleic acid- 4 ml

Benzyle benzoate- 25 ml

Water - 120 ml

Prepare a lotion. Label: Use as directed.

Liquid Calciferol- 0.12 ml

Glycerine- 0.30ml

water upto 4 ml

Send 30 ml

Prepare a emulsion.

Label: Take a tablespoonful twice a day.

Sodium salicylate- 1 g

Sodium bicarbonate- 2 g

Ferric chloride- 15 ml

Water upto 200 ml

Phenacetin- 3 g

Caffeine- 1 g

Syrup of Orange- 12 ml

Water upto 90 ml

Fiat misture; Label: Take a tablesponful with milk when pain
is severe.

Cetrimide- 0.5 g

Cetostearyl alcohol- 5.5 g

Soft paraffin- 5 g

Liquid Paraffin- 14 g

Water- 25 g

Apply to the skin twice a day.

Sodium salicylate- 4 g

Caffeine citrate- 2 g

Liquid extract of liquorice- 4 ml

water to 90 ml.


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