Pharmacology
(7 votes)
From the past five years question papers I could find out the following topics
which are commonly asked, in pharmacology the repeated questions are very less
every time we could expect the new questions so its better to have a greater insight
into all the topics.
I. Following are the general essay questions for 10
or 12 marks.
1. Different types of antagonisms with examples
2. Describe phase I and phase II reactions of metabolic biotransformation
of drugs.
3. Drug action mechanism types especially G- coupled type
4. Drug transport across biological membranes
5. Discuss pharmacogenetic factors influencing drug action
6. Describe drug interactions resulting from altered absorption or metabolism
in GIT.
7. Mention different CNS chemical mediators. Discuss the distribution and functions
of Noradrenaline and Dopamine.
8. Classify cholinergic agonists and antagonists based on receptor concept with
examples.
9. Give an account of location, function and transducer mechanisms of the different
subtypes of alpha and beta receptors.
10. Explain most important signs and stages of general anesthesia, mechanism
of action of general anesthetics.
11. Classify hypnotic drugs with examples. Discuss the mechanism of action and
uses of barbiturates. Why are they replaced benzodiazepines in the treatment
of insomnia?
12. What is depression? Classify the various drugs used in treatment of different
antidepressants. Discuss the mechanism of action and therapeutic uses of SSRI.
13. Classify psychopharmacological agents with examples.
14. Mention behavioral changes resulting from excessive alcohol intake.
15. What are anxiolytic drugs? Classify drugs used in treating anxiety. Discuss
in detail the mechanism of action and uses of benzodiazepines?
16. What are anti-arrithymic agents? Classify these agents, mechanism of action
and also explain their relative merits and demerits.
17. What is heart failure? Classify drugs used in congestive heart failure.
Discuss the mechanism of action, clinical uses and adverse effects of a natural
drug used in CHF.
18. What are anticoagulants? Classify agents used in the treatment of coagulation
disorders and explain the mechanism of action and adverse effects of different
anticoagulants.
19. What is obesity? Explain the role of different antihyperlipedemic drugs
giving their mechanism of action and effects.
20. Classify diuretics. Describe mode of action and toxic effects of
high ceiling diuretics and carbonic anhydrase inhibitors.
21.Mechanism of action of thiazide and loop diuretics
and Why Benzthiazide is mixed with Triamterene in an antidiuretic formulation
II . Differentiation and Comparison questions: (6
or 8 marks)
• Compare main Pharmacological actions of barbiturates
and benzodiazepines
• Comparison of digitalis and quinidine activity on heart
• Differences between antipsychotic and anxiolytic agent.
III. Write about the following: (6 or 8 marks)
• Therapeutic uses and toxicity of chelating agents
• Different routes of administration.
• Therapeutic status of ACE inhibitors.
• Mechanism of action and Therapeutic uses of benzodiazepines.
• Advantages of nonsystemic antacids.
• Uses and abuses of laxatives.
• Side effects of tricyclic antidepressants
• Habit forming drugs
• Action of quinidine on heart.
• Mechanism of action of tricyclic antidepressants.
• Mode of action of bronchodilators.
• Effects of digitalis in CHF
• Symptoms of poisoning from opiates
• Mechanism of antipsychotic effect of haloperidol
• SAR of barbiturates and Benzodiazepines.
• Pharmacotherapy of hypertension.
• Positive intortropic drugs
• Drugs treated for alcohol addiction
• Plasma substitutes
• Adrenergic B- blockers
• Dates vasomotor reversible phenomenon
IV. Short notes on pharmacolgy, mechanism of action
and therapeutic uses of the following (4 or 6 marks)
|
Aspirin
|
Glyceryl trinitrate
|
Clonidine
|
|
Atropine
|
Streptokinase
|
Dicyclomine
|
|
Atenolol
|
Verapamil
|
Buprenorphine
|
|
Caffeine
|
Phenytoin
|
Isosupurine
|
|
Nimesluide
|
Thiopentane sodium
|
Timolol
|
|
Diazepam
|
Succinyl choline
|
Spironolactone
|
|
Digoxin
|
Lithium Carbonate
|
Frusemide
|
|
Digitalis glycoslides
|
Irritant purgatives
|
Fluoxetine
|
|
Ethacrynic acid
|
Chlorpromazine
|
Codeine
|
|
Atorvastatin
|
Enalapril
|
Clonazepam
|
V Write a short note on the following:
|
Drug dependence
|
Unwanted effects of drugs
|
Tyrosine kinase receptors
|
|
Drug tolerance
|
Carcinogenicity and Mutagenecity
|
Opiate receptors
|
|
Withdrawal effects
|
Uptake mechanisms- Reuptake of catecholamines
|
Cyclooxygenase inhibitors
|
|
Enzyme induction
|
Neuroleptics
|
MAO inhibitors
|
|
Therapeutic index, Biological half life
|
Non depolarizing skeletal muscle relaxants
|
Cholinesterase inhibitors
|
|
SAR of drugs
|
Preanasthetic medication
|
B-Blockers.
|
|
Synergism
|
Urinary antiseptics
|
Ganglionic stimulants
|
|
Tachyphylaxis
|
Alcoholism
|
Local anesthetics
|
|
Counter irritants
|
Antacids
|
Expectorants
|
|
Antidiuretics
|
Analeptics
|
Demulcents
|
- santosh kumar. JH's blog
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...........good work.......
...........good work.......
Supriya vavilapalli
THE COGNITIVE MOLECULES
http://www.pharmainfo.net/supriya-vavilapalli
Dear Santosh
Great initiative,
Your blog link is sent to all our students appearing for the exam, Hope they may use the opportunity!
Good Luck for your exams too.
Regards
ESWAR :-)
Thank you very much Sir.....
Thank you very much Sir.....
Regards,
Santosh Kumar
http://www.pharmainfo.net/santosh-kumar-jh
dear santosh.. Good blog..1st
dear santosh..
Good blog..1st chap is very important..You should be thorough enough..Last year we got a question on Tachyphylaxis so better focus more on drug interactions..
Sirisha Pingali http://www.pharmainfo.net/sirisha/biography
Yes, first chapter is the
Yes, first chapter is the basic chapter... We should always get our basics right....
Regards,
Santosh Kumar
http://www.pharmainfo.net/santosh-kumar-jh
Great blog mate. Very useful
Great blog mate. Very useful for preparing for semester exams (especially one day batters ;))
Regards,
Niklesh Rao V
ATHARVANA
I hope this could really
I hope this could really strengthen their batting....
Regards,
Santosh Kumar
http://www.pharmainfo.net/santosh-kumar-jh
Dear Sir, Really it is a
Dear Sir,
Really it is a worthy blog.
Thank you for providing such info.
Regards,
Aishwaray
Regards
V.B.S.Aishwarya
BLOGGING BEES’s
Thank you..... If possible
Thank you.....
If possible please forward this blog link to all your friends who are appearing for the exam this could really help them....
Regards,
Santosh Kumar
http://www.pharmainfo.net/santosh-kumar-jh
Dear... Good
Dear...
Good efforts.....important for the exam point of view for your selective revision....Will help many to fetch good marks!!
Regards,
Faria Zarrin
Team: BLOGBUSTERS
My Page :
http://www.pharmainfo.net/zarrinfaria/biography
My Team:
http://www.pharmainfo.net/blog/blogbusters
Thank you Zarin for your
Thank you Zarin for your appreciation.. Its really encouraging...
Regards,
Santosh Kumar
http://www.pharmainfo.net/santosh-kumar-jh
Good collection.
Good collection in time of need!!!
keep it up.
Regards Kranthi http://www.pharmainfo.net/kranthikumar/biography
Hope you make the best
Hope you make the best use of it....
If possible forward this link to all your friends...who are appearing for the semester exam.. It could really help them also...
Regards,
Santosh Kumar
http://www.pharmainfo.net/santosh-kumar-jh