Hello friends, Feeling very happy to see the active participation of every one with their blogs,queries and answers. This month second half goes on with anhidrotics Have you ever imagined what happens if the temperature increases above 40 degrees or 45 degrees or how our body reacts for that? Before knowing the answer let us know what is an anhydrotic?

The substance which suppresses sweating is called anhydrotic or antiperspirants.

Coming to the answer for the above question in order to resist the excess heat our body produces sweat and controls but if excessive sweat is produced (hyperhidrosis) then what? During those situations these ANHIDROTICS are used. Mechanism: These drugs block the sweat ducts on the skin surface and certain drugs like formalin forms keratin plugs in the orifices of the skin there by stops the sweat. Anhidrotics are of two types: Systemic anhidrotics: Anticholinergics like belladonna alkaloids and methatheline. Local anhidrotics: Aluminum salts, formalin, glutaraldehyde and esters of hyosine. Heat exhaustion: In tropical countries heat will be dissipated as sweat and at times even the heat regulatory mechanisms may fail. Hence most of the water will be lost along with the some amount of salts .This is Anhydrotic heat exhaustion also called as Tropical anhydrotic asthenia where in, there will be a depression in sweating, exhaustion and vesicular skin lesions. Do u know...? * Eccrine sweat glands are innervated by sympathetic nerves but they are physiologically cholinergic. * Rabbits have sweat glands around their lips. * Tropical people excrete salt by lowering the levels of salt in the sweat and urine, by increasing the production of aldosterone. * Pigs do not sweat but in order to protect themselves from heat they stay in mud or water. * Adiaphoresis, Ischidrosis, Hypohidrosis, Oligidria, Oligohidrosis--- all these are related to anhidrosis.

REFERENCE:

http://www.pharmaceuticalu.com/heat-disorders-anhidrotic-heat-exhaustion/ dated 31st july 2011.

R.S.Satoskar S.D. Bandarkar,21st edition,popular prakashan private limited, sourabh printers.