Excipients

Modified excipients

There are several reports indicating that the peformance of a pharmacuetical dosage form is influenced by the changes in suppliers of the same excipient due to the variations in physicochemical properties and quality of excipient. There is increased demand for excipients with pre-determined specifications to control the physical properties of excipients like size, shape, tecture, density and moisture content. Spray dried excipients improves the flow property and freeze dried excipients enhances the dissolution rate.

Natural gums in drug formulations

There are polymers like proteins, enzymes and polysaccharides which are used in preparing various pharmaceutical products. And other natural gums like acacia, agar, carragenan, gelatin, isphagula which are widely used like emulsifying agent etc. When sea weeds are treated with bases it gives alginic acid,