Evaluation of Hibiscus syriacus L. flowers for wound healing activity in rats
Publication Type:
Conference ProceedingsSource:
National Conference on Recent Advances in Chemical Sciences, Bikaner, p.Acceptance of research paper for poster presentation on 4th Oct, 2008 (2008)Abstract:
Wound healing is the process of repair that follows injury to the skin and other soft tissues. Following injury, an inflammatory response occurs and the cells below the dermis begin to increase collagen production. Later, the epithelial tissue is regenerated
Wound care and maintenance involve a number of measures such as dressing and
Administration of painkillers, anti-inflammatory agents, healing promoting drugs etc. It
Runs through a number of phases such as coagulation, inflammation, granulation, fibroplasias, collagenation, would contraction and epithelization. Hibiscus syriacus L. (Malvaceae) well known drug in the system of Ayurveda system of Medicine. The search of Ayurvedic literature revealed the uses of Hibiscus syriacus L in wound healing. It is reported to possess diverse physiological properties. The leaves are diuretic, expectorant and stomachic. A decoction of the flowers is diuretic, ophthalmic and stomachic. It is also used in the treatment of itch and other skin diseases, dizziness and bloody stools accompanied by much gas. The bark contains several medically active constituents, including mucilage, carotenoids, sesquiterpenes and anthocyanidins. A decoction of the root bark is antiphlogistic, demulcent, emollient, febrifuge, haemostatic and vermifuge. It is used in the treatment of diarrhoea, dysentery, abdominal pain, leucorrhoea, dysmenorrhoea and dermaphytosis. . Since inflammation precedes the process of healing, drugs affecting inflammation are known to slow down the healing.
Since inflammation precedes the process of healing, drugs affecting inflammation are known to slow down the healing. A treatment could influence the healing of wound by intervening into anyone of many phases of wound healing. Conventional treatment includes keeping the wound clean, dry and covered. The present study was planned to assess the efficacy of this indigenous drug on some biochemical parameters related to wound healing in rats.