Malcolm J. D'Souza, Ph.D.

2010
Use of the Simple and Extended Grunwald-Winstein Equations in the Correlation of the Rates of Solvolysis of Highly Hindered Tertiary Alkyl Derivatives, D'Souza, Malcolm J., and Kevill Dennis N. , Current Organic Chemistry, p.in press, (2010)
2009
Grunwald-Winstein Analysis: Solvolysis of Isopropyl Chloroformate Revisited, D’Souza, M. J., Reed D. N., Erdman K. J., Kyong J. B., and Kevill D. N. , International Journal of Molecular Sciences, Volume 10, p.862-879, (2009)
Structure Activity Relationship (SAR) patterns observed within a series of unrelated common consumer drugs, D’Souza, M. J., Koyoshi F., and Everett L. M. , Bioinformatics, Computational Biology, Genomics, and Cheminformatics, p.1-6, (2009)
Extracting Relevant Information from FDA Drug Files to Create a Structurally Diverse Drug Database Using KnowItAll®, D'Souza, M. J., and Koyoshi F. , Pharmaceutical Reviews, Volume 7, Issue 3, (2009)
2008
KnowItAll® Consumer Drug Database, J., D'Souza M. , Bio-Rad's Experimental ADME/Tox Databases, 2008, USA, (2008)
Extended Grunwald-Winstein Analysis - LFER Used to Gauge Solvent Effects in p-Nitrophenyl Chloroformate Solvolysis, D’Souza, M. J., Shuman K. E., Carter S. E., and Kevill D. N. , International Journal of Molecular Sciences, Issue 9, p.2231-2242, (2008)
Correlation of the Rates of Solvolysis of Two Arenesulfonyl Chlorides and of trans-β-Styrenesulfonyl Chloride — Precursors in the Development of New Pharmaceuticals, Ryu Z. H., Lee D’Souza Yaakoubd Feld Kevill S. W. M. J. , International Journal of Molecular Sciences, Volume 9, p.2639-2657, (2008)
Concerted Solvent Processes for Common Sulfonyl Chloride Precursors used in the Synthesis of Sulfonamide-based Drugs, D’Souza, M. J., Yaakoubd L., Mlynarski S. L., and Kevill D. N. , International Journal of Molecular Sciences, Volume 9, p.914-925, (2008)
Correlation of the Rates of Solvolysis of Acetyl Chloride and α-Substituted Dervivatives, D’Souza, M. J., Ryu Z. H., Park B. –C., and Kevill D. N. , Canadian Journal of Chemistry, Issue 86, p.359-367, (2008)
Sixty Years of the Grunwald-Winstein Equation: Development and Recent Applications, Kevill, D. N., and D’Souza M. J. , Journal of Chemical Research, p.61-66, (2008)
2007
KnowItAll® U System - Software Reviews, D’Souza, M. J. , Chemistry World, Volume 4, Issue 11, p.70-72, (2007)
Consideration of the Factors Influencing the Specific Rates of Solvolysis of p-Methoxyphenyl Chloroformate, D’Souza, M. J., Reed D., Koyoshi F., and Kevill D. N. , International Journal of Molecular Sciences, Volume 8, p.788-796, (2007)
Correlations of the Specific Rates of Solvolysis of Aromatic Carbamoyl Chlorides, Chloroformates, Chlorothionoformates, and Chlorodithioformates Revisited., Kevill, D. N., Koyoshi F., and J. D’Souza M. , International Journal of Molecular Sciences, Volume 8, p.346-362, (2007)
Rate and Product Studies in the Solvolyses of Methanesulfonic Anhydride and a Comparison with Methanesulfonyl Chloride Solvolyses., Kevill, D. N., Ryu Z. H., Niedermeyer M. A., Koyoshi F., and D’Souza M. J. , Journal of Physical Organic Chemistry, , Volume 20, p.431-438, (2007)
2006
Rate and Product Studies in the Solvolyses of N,N-dimethylsulfamoyl and 2-Propanesulfonyl Chlorides., Kevill, D. N., Park B. C., Park K. H., D’Souza M. J., Yaakoubd L., Mlynarski S. L., and Kyong J. B. , Organic and Biomolecular Chemistry, Volume 4, p.1580-1586, (2006) Abstract
Correlation of the Rates of Solvolysis of 2-Furancarbonyl Chloride & Three Naphthoyl Chlorides., D’Souza, M. J., Boggs M. E., and Kevill D. N. , Journal of Physical Organic Chemistry, Volume 19, Issue 3, p.173-178, (2006)
2005
KnowItAll® - Software Reviews, D’Souza, M. J. , Chemistry World, Volume 2, Issue 9, p.70-71, (2005)
2004
Correlation of the Rates of Solvolysis of Benzoyl Fluoride and a Consideration of Leaving-Group Effects., Kevill, D. N., and D’Souza M. J. , Journal of Organic Chemistry, Volume 69, Issue 21, p.7044-7050, (2004)
2003
Correlation of the Rates of Solvolysis of 2-Thiophenecarbonyl Chloride., D’Souza, M. J., Stant-Boggs M. E., White R., and Kevill D. N. , Journal Chemical Research (S), Issue 12, p.775-777, (2003)
2002
Correlation of the Rates of Solvolysis of n-Octylfluoroformate and a Comparison with n-Octylchloroformate Solvolysis, Kevill, D. N., and D’Souza M. J. , Journal Chemical Society Perkin Transactions 2, p.240-243, (2002)
Correlation of the Rates of Solvolysis of Benzoyl Chloride and Derivatives Using Extended Forms of the Grunwald-Winstein Equation., Kevill, D. N., and D’Souza M. J. , Journal of Physical Organic Chemistry , Volume 15, Issue 12, p.881-888, (2002)
2001
Concerning the Extent of Nucleophilic Participation in Solvolyses of Glucopyranosyl Derivatives, Kevill, D. N., and D’Souza M. J. , Journal of Physical Organic Chemistry, Volume 14, Issue 11, p.819-822, (2001)
2000
Solvolysis of N, N-dimethylthiocarbamoyl Chloride: Effect of sulfur-for-oxygen substitution upon kinetics and product partitioning, Kevill, D. N., Rudolph T. M., and D'Souza M. J. , Journal of Physical Organic Chemistry, Volume 13, Issue 4, p.192-196, (2000)