Abstract

Two widely faced challenges in oral drug delivery are pill-swallowing difficulty and delivery of unpalatable drugs.

“The two sweeteners when combined have a synergistic effect that is the sweetness of the combination is greater than the sum of the individual parts. This is true for most sweetener blends”

1. Introduction :

Medicinal chemistry, like synthetic chemistry, comprises both art and science.

It requires a comprehensive mind to collect and synthesize mountains of data, chemical and biological. It requires the instinct to select the right direction to pursue, and the intellect to plan and execute the strategy that leads to the desired compound.

Silicones (more accurately called polymerized siloxanes or polysiloxanes) are mixed inorganic-organic polymers with the chemical formula [R₂SiO]_n, where R is organic groups such as methyl, ethyl, and phenyl.

Topical preparations are used for the localized effects at the site of their application by virtue of drug penetration into the underlying layers of skin or mucous membranes.

A keloid is a benign, well-demarcated area of fibrous tissue overgrowth that extends beyond the original defect.

A hypertrophic scar is similar but remains confined to the initial defect and tends to resolve with time. An imbalance of matrix degradation and collagen biosynthesis resulting in excess accumulation of collagen in the wound has been postulated to be the primary biochemical features of this skin lesion.

Knowledge and applications of molecularly imprinted polymers (MIP), is rapidly developing, especially in the chemical analysis field, Molecular imprinting is a method of inducing molecular recognition properties in synthetic polymers in response to the presence of a template species during formation of the three-dimensional structure of the polymer.

Introduction

Also known as….       

Electron Paramagnetic Resonance (EPR)

Electron Magnetic Resonance (EMR)

The concept of Mouth Dissolving Drug Delivery System emerged from the desire to provide patient with more conventional means of taking their medication.

1. What is Sop