Abstract:

The need for delivering drugs to patients efficiently with minimum side effects has prompted pharmaceutical industries to be engaged in development of new drug delivery systems. Pediatric and geriatric patients find it difficult to swallow solid dosage forms like tablets. Mouth dissolving tablet that dissolve or disintegrate rapidly in oral cavity result in solution, is an ultimate remedy for this problem. In addition they give pleasing mouth feeling. MDT has advantages such as patient compliance, quick onset of action, improved bioavailability, etc.

Decisions to approve, prescribe and consume medicines involve risk/benefit assessments by regulatory agencies, health care professionals and consumers. For serious or life threatening conditions, drugs with higher risks for adverse effects or for serious adverse effects are sometimes acceptable. For example, some life-saving cancer chemotherapies are known human carcinogens. However, if one is suffering from a life threatening tumor, a 5% risk of a secondary, treatment-related tumor is generally considered acceptable.